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It was first made by Union Chimique Belge in and was approved for sale by Pfizer in the United States later that year.
Generic alternatives may be available.
What special precautions should I follow?
See also: Atarax drug interactions in more detail.
The T max of hydroxyzine is about 2.
Cetirizine, although less sedating, is non- dialyzable and possesses similar anti-histaminergic properties.
Use effective birth control, and tell your doctor if you become pregnant during treatment.
Hydroxyzine should be administered carefully in the elderly with consideration given to possible reduced elimination.
Do not let anyone else take your medication.
This list is not complete and other drugs may interact with hydroxyzine.
Be sure to mention any of the following: antihistamines; azithromycin Zithromax, ZMax , certain antidepressants such as citalopram Celexa and fluoxetine Prozac, Sarafem, Selfemra ; medications for anxiety; certain medications for arrhythmias such as amiodarone Cordarone, Nexterone, Pacerone, , procainamide, quinidine in Nuedexta , and sotalol Betapace, Sorine, Sotylize ; barbiturates; clarithromycin Biaxin, in Prevpac ; droperidol Inapsine ; erythromycin Eryc, Ery-Tab, PCE, others ; gatifloxacin; certain medications for mental illness such as chlorpromazine, clozapine Clozaril, Fazaclo ODT, Versacloz , iloperidone Fanapt , quetiapine Seroquel , and ziprasidone Geodon ; meperidine Demerol ; methadone Dolophine, Methadose ; moxifloxacin Avelox ; medications for pain; ondansetron Zofran, Zuplenz ; pentamidine Nebupent, Pentam ; and medications for seizures, sedatives, sleeping pills, and tranquilizers.
In a comparative study with lorazepam on memory effects, patients who had taken hydroxyzine experienced sedative effects like drowsiness, but recalled that they felt capable, attentive and able to continue with a memory test under these conditions.
Irish Medicines Board.
Talk to your doctor before breastfeeding while using this medicine.
Oxford [Oxfordshire]: Oxford University Press.
It is also used together with other medications given for anesthesia.
Analogues of hydroxyzine include buclizine , cetirizine , cinnarizine , cyclizine , etodroxizine , meclizine , and pipoxizine among others.
Oral: 50 to mg orally 4 times a day Parenteral: 50 to mg IM immediately, then every 4 to 6 hours as needed Comments : -Use should be periodically reassessed.
Hydroxyzine may be used to treat allergic skin reactions such as hives or contact dermatitis.
See also: Hydroxyzine side effects in more detail.
It is important for you to keep a written list of all of the prescription and nonprescription over-the-counter medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements.
Oral: 25 mg orally 3 to 4 times a day Use: Management of pruritus due to histamine-mediated pruritus and allergic conditions e.
However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule.
Atypical antipsychotics Olanzapine Quetiapine Risperidone , etc.
Talk to you doctor before using hydroxyzine if pregnant or breastfeeding.
Gabapentin Gabapentin enacarbil Mirogabalin Phenibut Pregabalin.
It also acts as an antihistamine that reduces the natural chemical histamine in the body.
Trazodone Tricyclic antidepressants Amitriptyline Doxepin Trimipramine , etc.
Hydroxyzine exhibits anxiolytic and sedative properties in many psychiatric patients.
Since hydroxyzine also reduces activity in the central nervous system, it can be used as a sedative to treat anxiety and tension.
Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
Hydroxyzine side effects in more detail.
From Wikipedia, the free encyclopedia.
In other cases, the usage of hydroxyzine is as a form of non-barbiturate tranquilizer [12] used in the pre-operative sedation and treatment of neurological disorders, such as psychoneurosis and other forms of anxiety or tension states.
Hydroxyzine Dosage Medically reviewed by Drugs.
Higher concentrations are found in the skin than in the plasma.
Hydroxyzine was found to have no adverse effects on memory in relation to lorazepam , which caused several deficiencies in the capacity of memory storage.
Somnolence with or without vivid dreams or nightmares may occur in users with antihistamine sensitivities in combination with other CNS depressants.
Tell your doctor about all your current medicines and any you start or stop using.
Stop using Atarax and call your doctor at once if you have a serious side effect such as tremors, confusion, seizures, or restless muscle movements in your eyes, tongue, jaw, or neck.
Do not take in larger or smaller amounts or for longer than recommended.
This is not a complete list of side effects and others may occur.
Tell your doctor if any of these symptoms are severe or do not go away: dry mouth constipation especially in older adults confusion especially in older adults dizziness headache Some side effects can be serious.
Tell your doctor about all medicines you use, and those you start or stop using during your treatment with this medicine.
Hydroxyzine may cause other side effects.
Do not drive a car or operate machinery until you know how this medication affects you.
See also: Atarax dosage information in more detail.
Patient Advice : -Inform patients that this drug may cause drowsiness, and they should avoid driving or operating machinery if these side effects occur.
Do not breastfeed while taking hydroxyzine.
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them.
Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.
To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location — one that is up and away and out of their sight and reach.
IUPAC name.
Use of hydroxyzine for premedication as a sedative has no effects on tropane alkaloids, such as atropine , but may, following general anesthesia, potentiate meperidine and barbiturates , and use in pre-anesthetic adjunctive therapy should be modified depending upon the state of the individual.
Follow all directions on your prescription label.
Do not take more or less of it or take it more often than prescribed by your doctor.
Do not take extra medicine to make up the missed dose.

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Measure Atarax syrup with a special dose-measuring spoon or cup, not a regular table spoon.
Serotonin receptor modulators.
To make sure you can safely take Atarax, tell your doctor if you have any of these other conditions:.
While there are reports of the "hallucinogenic" or "hypnotic" properties of hydroxyzine, several clinical data trials have not reported such side effects from the sole consumption of hydroxyzine, but rather, have described its overall calming effect described through the stimulation of areas within the formatio reticularis.
Hydroxyzine can also be used for the treatment of allergic conditions , such as chronic urticaria , atopic or contact dermatoses , and histamine -mediated pruritus.
IV compatibility : -Incompatible: Aminophylline, benzylpenicillin salts, chloramphenicol sodium succinate, dimenhydrinate, doxorubicin hydrochloride in a liposomal formulation , thioridazine, and some soluble barbiturates General : -This drug has demonstrated primary skeletal muscle relaxation and antispasmodic properties experimentally.
Gabapentin Gabapentin enacarbil Phenibut Pregabalin.
Your doctor will probably tell you not to take hydroxyzine.
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Tetracyclic antidepressants Mianserin Mirtazapine , etc.
Other drugs may interact with hydroxyzine, including prescription and over-the-counter medicines, vitamins, and herbal products.
Hydroxyzine is a member of the diphenylmethylpiperazine class of antihistamines.
You should not take this medicine for longer than 4 months.
Do not use Atarax without telling your doctor if you are pregnant.
Do not start a new medication without telling your doctor.
Atropine Diphenhydramine Hydroxyzine very mild Hyoscyamine Scopolamine.
Cerium oxalate Dexamethasone Lorazepam Midazolam Propofol.
It is important to keep all medication out of sight and reach of children as many containers such as weekly pill minders and those for eye drops, creams, patches, and inhalers are not child-resistant and young children can open them easily.
Ask your doctor before taking hydroxyzine with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.
Tell your doctor about all medications you use.
Hydroxyzine can cause a serious heart problem, especially if you use certain medicines at the same time, including antibiotics, antidepressants, heart rhythm medicine, antipsychotic medicines, and medicines to treat cancer, malaria, HIV or AIDS.
Get emergency medical help if you have any of these signs of an allergic reaction to Atarax: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Do not use this medicine in larger or smaller amounts or for longer than recommended.
Before Prozac: the troubled history of mood disorders in psychiatry.
Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
Hydroxyzine is used in adults and children to relieve itching caused by allergic skin reactions.
Typical antipsychotics Chlorpromazine Thioridazine , etc.
Hydroxyzine dosage information in more detail.

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Histamine can produce symptoms of sneezing and runny nose, or hives on the skin.
Hydroxyzine could harm the unborn baby or cause birth defects.
If you do not have a dose-measuring device, ask your pharmacist for one.
See also: Atarax side effects in more detail.
Unless your doctor tells you otherwise, continue your normal diet.
Histamine can produce symptoms of itching, or hives on the skin.
Centers for Medicare and Medicaid Services.
Taking this medicine with other drugs that make you sleepy can worsen this effect.
Before using Atarax, tell your doctor if you regularly use other medicines that make you sleepy such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety.
In case of overdose, call the poison control helpline at
It usually is taken three or four times a day.
However, you should not flush this medication down the toilet.
Textbook of Anxiety Disorders.
See also: Hydroxyzine dosage information in more detail.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Keep this medication in the container it came in, tightly closed, and out of reach of children.
Overdose symptoms may include severe drowsiness, nausea, vomiting, uncontrolled muscle movements, or seizure convulsions.
Hydroxyzine , sold under the brand names Atarax among others, is a medication of the antihistamine type.
Hydroxyzine comes as capsules, tablets, a syrup, and suspension to take by mouth.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Hydroxyzine drug interactions in more detail.
This medication may be prescribed for other uses.
Hydroxyzine may cause birth defects.
Follow the directions on your prescription label.
Stop taking this medicine and call your doctor right away if you have sudden skin redness or a rash that spreads and causes white or yellow pustules, blistering, or peeling.
Storage Requirements : The manufacturer product information should be consulted.
Central nervous system problems such as hallucinations or confusion have been observed in rare cases, attributed mostly to overdosage.
It also works by decreasing activity in the brain.
Your doctor may occasionally change your dose.
The effect of hydroxyzine is notable in 30 minutes.
If you experience any of the following symptoms, call your doctor immediately: unintentional trembling or shaking movements seizures If you experience any of the following symptoms of a serious skin condition; stop taking hydroxyzine and call your doctor immediately: rash pus-filled, blister-like sores lesions , areas of swelling and redness on the skin, and fever Hydroxyzine may cause other side effects.
Hydroxyzine is synthesized by the alkylation of 1- 4-chlorobenzhydryl piperazine with 2- 2-Chloroethoxy ethanol: [41].
The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records.
It could harm the unborn baby.
This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.

hydroxyzine atarax


Our Online pharmacy Be careful if you drive or do anything that requires you to be alert.
You should bring this list with you each time you visit a doctor or if you are admitted to a hospital.
Other studies have suggested that hydroxyzine acts as an acute hypnotic, reducing sleep onset latency and increasing sleep duration — also showing that some drowsiness did occur.
Hydroxyzine is in a class of medications called antihistamines.
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Similarly, the use of sedating drugs alongside hydroxyzine can cause oversedation and confusion if administered in large amounts—any form of treatment alongside sedatives should be done under supervision of a doctor.
In rare cases, hydroxyzine may cause a severe skin reaction.
Hydroxyzine is used in the treatment of itchiness , anxiety , and nausea due to motion sickness.
Get emergency medical help if you have signs of an allergic reaction to hydroxyzine: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
They can add to sleepiness caused by Atarax.
The administration of hydroxyzine in large amounts by ingestion or intramuscular administration during the onset of pregnancy can cause fetal abnormalities—when administered to pregnant rats, mice and rabbits, hydroxyzine caused abnormalities such as hypogonadism with doses significantly above that of the human therapeutic range.
This was observed more in female patients, who also had greater hypnotic response.
Store it at room temperature and away from light, excess heat and moisture not in the bathroom.
Shake the oral suspension liquid well just before you measure a dose.
Hydroxyzine has shown to be as effective as the benzodiazepine drug bromazepam in the treatment of generalized anxiety disorder.
In other projects Wikimedia Commons.
Studies have also been conducted which show that long-term prescription of hydroxyzine can lead to tardive dyskinesia after years of use, but effects related to dyskinesia have also anecdotally been reported after periods of 7.
Before taking hydroxyzine, tell your doctor and pharmacist if you are allergic to hydroxyzine, cetirizine Zyrtec , levocetirizine Xyzal , any other medications, or any of the ingredients in hydroxyzine preparations.
It works by blocking the action of histamine a substance in the body that causes allergic symptoms.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Atarax only for the indication prescribed.
Interactive image.
It is also used alone or with other medications in adults and children to relieve anxiety and tension.
The effect of hydroxyzine has also been tested on the ability of humans in the registration and storage of memory, and was used in comparison with relatively safe drugs, such as lorazepam, to illustrate the effects of benzodiazepines, which are thought to have adverse effects on the capacity of memory storage.
The drug is available in two formulations , the pamoate and the dihydrochloride or hydrochloride salts.
The Atarax brand name has been discontinued in the U.
Other contraindications include the administration of hydroxyzine alongside depressants and other compounds which affect the central nervous system.
This side effect is more likely to occur in people with pre-existing cardiac disease, or with the use of other medicines known to prolong the QT interval.
Shake the suspension well before each use to mix the medication evenly.
Older adults should not usually take hydroxyzine because it is not as safe as other medications that can be used to treat the same condition.

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